Normally, the nitrogen oxide (NO) penetrates inside cavernosal smooth muscle cells where it activates the GMPc, which in turn causes a release of calcium ions and relaxation. Erectile dysfunction has been observed that there is decreased bioavailability of NO in the cavernous smooth muscle cells.

  The formula Erectosan based on the pathophysiology of erectile dysfunction offers of L-citrulline and Maritime pine extract thus helps to increase NO production through increased bioavailability of L-arginine, an increase of NO synthase (NOS) and an increase of its production GMPc. H L- arginine is involved in the pathway synthesis of NO while of L-citrulline is a precursor of the endogenous production of L-arginine by the body. To sea pine extract has been found that it can increase the production of eNOS in erectile dysfunction. Additional features antioxidant protecting cells of the reproductive system of men from oxidative stress.