More specifically, inositol is known as vitamin B8, a natural isomer of glucose. It is an important key intermediate element of the second messengers, but also a predominant component of phospholipids of cell membranes involved in many biological processes.
Its unique chemical structure allows it to get in and out of the cells, playing its catalytic role. Its role is important in how neurotransmitters work in the brain and in the body, including reversing serotonin detoxification, thus regulating serotonin activity.
It is also important for switching signals for calcium and insulin.
It is a component of the biological information exchange system.
Inositol contributes to information processing within the cell, e.g. of the biological information contained in the hormones.
The second messengers are molecules inside cells that act to transmit signals from a receptor to a target.
The term, second messengers, was devised by the discovery of these substances in order to distinguish them from hormones and other molecules that function outside the cell as "first messengers" in the transmission of biological information.
A large number of molecules have been characterized as second messengers, including molecules derived from phospholipids (inositol triphosphate).
A general second-messenger system can be divided into four stages.
First stage: the agonist activates a receptor bound to the membrane.
Second Stage: Activated Protein G produces a key operator.
Stage Three: the main effect stimulates the synthesis of the second messenger.
Stage Four: The second messenger activates a certain cellular process.
Receptors that bind to the G-protein for the messenger PIP2 system (diphosphate phosphatidyl inositol) produce two effectors, phospholipase C (PLC) and phosphoinositide 3-kinase (PI3K).
The PLC as an operator produces two different second messengers, inositol triphosphate (IP3) and diacylglycerol (DAG).
The IP3 (inositol triphosphate) is soluble and diffuses freely to the cytoplasm. As a second messenger, it is recognized by the inositol triphosphate receptor (IP3R), a Ca2 + channel in the membrane of the endoplasmic reticulum (ER), which stores intracellular Ca2 +.
The binding of (inositol triphosphate) IP3 to its receptor releases Ca2 + from the endoplasmic reticulum into the normally Ca2 + -based cytoplasm, which then activates the signaling of various Ca2 + manifestations. In particular, in blood vessels, increasing Ca2 + concentration from IP3 triphosphate releases nitrogen oxide, which then diffuses into smooth muscle tissue and causes relaxation.
In 1984, with a paper published in Nature, inositol triphosphate is officially ranked in the second cell messengers messengers. Until 2010, the volume of literature exceeds 20,000 publications in many scientific journals.
Its role starts in biology, engages in medicine (in specialties such as neurology, endocrinology and pathology), and is realized in pharmacy.
Finally, the role of inositol in the nervous system is decisive.
WARNINGS:
• Do not exceed the recommended daily allowance.
• M / V should not be used as a substitute for a balanced diet.
• Keep out of the reach of children.
• This product is not intended for the prevention, treatment or cure of a human disease.
• Consult your doctor if you are pregnant, breast-feeding, undergoing medication or experiencing health problems.
