Triadenor contains a rational combination of ingredients that appear to help better treat depression, administered either in combination with or without medication.
Despite the numerous therapeutic interventions and options that have significantly contributed to reducing the symptomatology of depression, approximately 50% of the patients are resistant to treatment. Even more, the failure of the depressed person to return to full function, reduced tolerance to medication and poor compliance with medication, necessitate a new approach to better treat depression (7).
Patients with depression have proven neurodevelopmental disorder associated with reduced dopaminergic, serotoninergic and norepinephrine activity, increased concentrations of cytokines and inflammation, and decreased synthesis of neurotrophic factors.
Triadenor contains ingredients that restore and correct human body mechanisms that are associated with the onset of depressive symptoms.
Triadenor contains Quatrefolic (L-methyltetrahydrofolate-1-glucosamine sodium) which corrects one of the major problems in depression that is L-methyltetrahydrofolate deficiency which is required for the formation of neurotransmitters and is due either to reduced folic acid synthesis or the substrate necessary for this purpose.
The concomitant presence of S-Adenosyl Methionine (SAMe) as a methyl donor in the biosynthesis of neurotransmitters from the substrate of L-methyltetrahydrofolate additionally contributes to the restoration of their production. The action of N-Acetyl-Cysteine is associated with controlling the inflammatory process by increasing glutathione synthesis, reducing cytokine types and specific neurotrophic activity.
Triadenor belongs to the Nutraceuticals team. These products are non-medicinal products that have a botanical or chemical-natural origin but their ingredients have proven scientifically significant benefits to human health. Nutraceuticals can be a new and important auxiliary approach to treating pathological conditions such as depression.
Each Triadenor tablet contains L-methyltetrahydrofolate-1-glucosamine sodium 400mcg equivalent to 215mcg Folic Acid, S-Adenosyl Methionine (SAMe) 200mg and N-Acetyl Cysteine 500mg.
It is noted that both S-Adenosyl Methionine (SAMe) and Folic Acid are included in the American Psychiatric Association's Guidelines for Depression as Supportive and Complementary Therapies.
Triadenor is packaged in 16 tablets and is available from pharmacies.
It is recommended to take one tablet a day with a small amount of water after a light meal.