Androgenetic alopecia

 

   The common form of hair loss is the so-called androgenetic alopecia (baldness). This alopecia affects both sexes. Alopecia affects people from adolescence and is continued for years. The fifty percent of men over 50 years old is estimated that they suffer from androgenetic alopecia, in women this happens after menopause. Hair loss in men comes gradually creating a characteristic “M” shape hairline. Although, there is hair loss at the crown and this is the distinction between partial and complete baldness.

   The hair loss pattern differentiate between the sexes. Men loose their hair completely. On the other hand women hair become thinner all over the head but the hairline doesn't recede and rarely leads to total baldness.

   In men androgenetic alopecia has been associated with high level of free testosterone and dihydrotesterone (DHT) and other medical conditions such as coronary heart disease, prostate enlargement, diabetes, hypertension. On the contrary women have hair loss due to polycystic ovary syndrome which leads to acne, irregular menstruation, hirsutism, weight gain.

   Physical examination through laboratory tests play a major role to diagnosis in patients with androgenetic alopecia. Experts have to pay attention on the level DHEA (dehydroepiandrosterone), iron and transrerrin saturation, thyrotropin level as well.

   Androgenetic alopecia is getting involved with a variety of genetic and environmental factors. Nevertheless, researchers havent understand these factors yet. The main reason of this kind of alopecia is andogens and particularly dihydrotestosterone. Generally androgens are extremely important for sexual development for men. In addition to this, both sexes have important functions such as regulating hair growth and sex drive.

   Androgens are responsible for the reduced cycle of hair growth and the growth of shorter and thinner strands of hair. Androgens destroy the majority of follicles. Therefore the hair replacement gets more and more time.

   The management of this disease may contain hormonal, non hormonal and surgical treatment. For male pattern baldness, non hormonal treatment is minoxidil. It has been proved that interfere with the mechanism of alopecia prolonging the anagen phase of the hair by increasing its lifetime. Treatment should be taken for six months at least. The use of the interruption may trigger the resumption of hair loss. Concerning men the hormonal treatment for androgenetic alopecia for men include finasteride. It is antiadrogono, inhibitor of 5-a-reductase and becomes opment by the mouth. The effectiveness rate reaches 90%, particularly at an early age and in the early stages of alopecia. For women, the hormonal therapy can be based on this substance after menopause. Women may also experience of disease using contraceptives when alopecia is caused by polycystic ovary syndrome. Substances of combating the disease in women is estrogen, progesterone, and spironolactone.

   In the first-line treatment should be included appropriate products that promise end of hair loss, regulating oily / dry skin of the scalp and gives density and health to the hair. There is a combination of products such as lotions, caps, shampoo, foam, which are equipped with the latest hair enforcement formula in order to strengthen hair.

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