The highest concentration of CoQ10 is found in the heart and liver tissue and is a key element of mitochondria. It plays a significant role in the body to produce energy in the mitochondria, helping to metabolize fats and carbohydrates, as well as maintaining the cell membrane elasticity. It also participates in the production of other key enzymes used for the production of Adenosine 5'-triphosphate (ATP), which is burned by the body for energy production but also for transporting energy between mitochondria and cells.

Yearly research has shown that beyond its contribution to energy production, CoQ10 supports the healthy functioning of the cardiovascular and immune system. In addition, CoQ10 is an effective lipid-soluble antioxidant that provides protection to the structure of vessels and other tissues from attack by free radicals but can also positively affect the aging process. Studies have demonstrated the importance of CoQ10 in maintaining a healthy intracellular activity while comparing its effectiveness with that of vitamin E, one of the most effective antioxidants.

NOW sells only the natural, 100% all-trans form of CoQ10 produced by natural fermentation and bought by the leading Japanese suppliers. This is considered to be the best and most natural form available. Differences in the absorption or use of CoQ10 products are mostly associated with oils added to CoQ10 powder within the softgel. These differences are much less important when the supplement is taken at the same time as other oils or supplements based on oils in the diet rather than between meals. Thus they still yield the benefits of increased absorption, even by taking CoQ10 in a vegetarian form.