Uterine fibroids (also known as leiomyomas or myomas) are among the most common benign uterine tumors and can affect up to 75-80% of women.
Fibroids appear from a young age and shrink with menopause. They vary according to their shape, size and position in the uterus.
Fibroids are estrogen- and progesterone-dependent uterine masses that arise from the smooth muscle cells of the uterus.
The wide range of symptoms includes: acute and chronic pelvic pain, constipation, polyuria, infertility, dyspareunia (pain and discomfort during sexual intercourse) and iron deficiency anemia due to heavy bleeding during menstruation (menorrhoea) but also less frequently in through the menstrual cycle.
Besides anemia, severe and prolonged blood loss represents the symptom with the greatest impact on quality of life in women with uterine fibroids.
Phydelis® is a new, innovative dietary supplement with vitamin D, epigallocatechin gallate (EGCG) and vitamin B6, which reduces heavy bleeding and the duration of menstruation and improves the quality of life of women with uterine fibroids.
The combination of vitamin D, EGCG and vitamin B6 (Phydelis®) provides a synergistic beneficial effect in the management of uterine fibroids. More specifically, vitamin D inhibits the proliferation of fibroid cells, as lower levels of 25-hydroxy-vitamin D3 have been found in women with fibroids compared to the healthy population.
Epigallocatechin gallate induces cell apoptosis reversing the progression of fibroids. It is the main catechin, accounting for >40% of the total catechin mixture of green tea, and exhibits various biological activities, including strong antioxidant and anti-inflammatory effects.
Finally, vitamin B6 offers hormonal balance.